The Great River Road follows Wisconsin State Highway 35 from Prescott south through Onalaska and La Crosse to Prairie du Chien and then follows all weather county roads to Cassville. From Cassville, Hwy. 133 meets US 61 at Tenneyson and carries the Great River Road to the Illinois line. Watch for the Great River Road signs marking the route.

Much of Wisconsin’s Great River Road is etched at the base of bluffs and adjacent to the river. It passes through many communities such as Onalaska, Holmen and Trempealeau. The road curves winding with the river, a drive to enjoy. The 30 mile stretch between Alma and Maiden Rock and 60 miles between La Crosse and Praire du Chien is considered to be one of the most scenic routes in America. Many waysides and overlooks provide an opportunity to stop, rest and photograph the river scenery.

The Great River Road is well-maintained and is beautiful in all seasons. A full map of the Great River Road can be found at